Structure of PDB 8h2t Chain D Binding Site BS02

Receptor Information
>8h2t Chain D (length=435) Species: 34073 (Variovorax paradoxus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYRDNPDAIRALVQDDRVHRDLYTSQELFELEQEHFFANTWNYVGHESQL
PKPGDWISNEIAGRPLIVARHSDGSVRAMMNRCAHKGSRLVNGPCGNTGK
FFRCPYHAWTFKTDGSLLAIPLKTGYENTALHECESAKGLTTLRYVRSHR
GFIFVKISDAGPDFDDYFGDSLSSIDNMADRSPEGELEIAGGCLRFMHQC
NWKMFVENLNDTMHPMVAHESSAGTAKRMWADKPEDEPKPMAVEQFAPFM
SDYKFFEDMGIRTYDNGHSFTGVHFSIHSKYKAIPAYDDAMKARYGEAKT
AQILGMARHNTVYYPNLTIKGAIQAIRVVKPISADRTLIESWTFRLKGAP
PELLQRTTMYNRLINSPFSVVGHDDLQAYRGMQAGLHASGNEWVSLHRNY
DPSELKGGEITTGGTNELPMRNQYRAWVQRMTETM
Ligand information
Ligand IDIAC
InChIInChI=1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)
InChIKeySEOVTRFCIGRIMH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6c1ccc2c(c1)c(c[nH]2)CC(=O)O
ACDLabs 12.01O=C(O)Cc2c1ccccc1nc2
CACTVS 3.370OC(=O)Cc1c[nH]c2ccccc12
FormulaC10 H9 N O2
Name1H-INDOL-3-YLACETIC ACID;
INDOLE ACETIC ACID
ChEMBLCHEMBL82411
DrugBankDB07950
ZINCZINC000000083860
PDB chain8h2t Chain D Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8h2t cryo-EM structure of a bacterial dioxygenase
Resolution2.59 Å
Binding residue
(original residue number in PDB)		N210 L211 D213 H216 P217 K322 Y362
Binding residue
(residue number reindexed from 1)		N208 L209 D211 H214 P215 K320 Y360
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0044237 cellular metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8h2t, PDBe:8h2t, PDBj:8h2t
PDBsum8h2t
PubMed37459330
UniProtC5CSP6

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