Structure of PDB 8h2h Chain D Binding Site BS02

Receptor Information
>8h2h Chain D (length=599) Species: 1358 (Lactococcus lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGAS
TKGILDDTADGFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPL
GIPTFTDKLIQEAVRIILESIYEPVFEDVSHGFRPQRSCHTALKTIKREF
GGARWFVEGDIKGCFDNIDHVTLIGLINLKIKDMKMSQLIYKFLKAGYLE
NWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKFDRESPERITP
EYRELHNEIKRISHRLKKLEGEEKAKVLLEYQEKRKRLPTLPCTSQTNKV
LKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHS
SQPARFLGYDIRVRRSGTIKRSGKVKKRTLNGSVELLIPLQDKIRQFIFD
KKIAIQKKDSSWFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFN
QLNYFAYLMEYSCLKTIASKHKGTLSKTISMFKDGSGSWGIPYEIKQGKQ
RRYFANFSECKSPYQFTDEISQAPVLYGYARNTLENRLKAKCCELCGTSD
ENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCFHCHRHVIHKHK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8h2h Functionalized graphene grids with various charges for single-particle cryo-EM.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		N450 Y457 S476
Binding residue
(residue number reindexed from 1)		N450 Y457 S476
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0003964 RNA-directed DNA polymerase activity
GO:0004519 endonuclease activity
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0006314 intron homing
GO:0006397 mRNA processing
GO:0006974 DNA damage response

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Molecular Function
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Biological Process
External links
PDB RCSB:8h2h, PDBe:8h2h, PDBj:8h2h
PDBsum8h2h
PubMed36344519
UniProtP0A3U0|LTRA_LACLC Group II intron-encoded protein LtrA (Gene Name=ltrA)

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