Structure of PDB 8fd7 Chain D Binding Site BS02

Receptor Information
>8fd7 Chain D (length=955) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPSAVTIKSWVDKMQEDLVTLAKTASGVHQLVDIYEKYQDLYTVEPNNAR
QLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYN
AKDDEPGSQRIKPVFIDDANFRRQVSYQHAAVHIPTDIYEGSTIVLNELN
WTSALDDVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKID
LYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLS
DDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYK
KGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKYNKDKKVRV
FTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPM
VLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQLI
LGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGV
GIPTINSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQD
ERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKIEETITQARYSE
TLKPDNFEESGYTFLAPRDYCSDLKPSDNNTEFLLNFNEFIDRKTPNNPS
CNTDLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPK
EAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSK
AVEIYIQGKLLKPAVVGIKIDVNSWIENFTKRNSDVMDCVILDDGGFLLM
ANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAASK
QSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHVEKLMNTNLIFIMVESK
GTCPCDTRLLIQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNVLEDYTDC
GGVSG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8fd7 Chain D Residue 1210 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fd7 Structural basis for Ca V alpha 2 delta :gabapentin binding.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		S263 S265 T333
Binding residue
(residue number reindexed from 1)		S227 S229 T297
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8fd7, PDBe:8fd7, PDBj:8fd7
PDBsum8fd7
PubMed36973510
UniProtP13806|CA2D1_RABIT Voltage-dependent calcium channel subunit alpha-2/delta-1 (Gene Name=CACNA2D1)

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