Structure of PDB 8epx Chain D Binding Site BS02

Receptor Information

>8epx Chain D (length=506) Species: 2070761 (Paucibacter aquatile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PYDHNAEADFAASEVARMLVADPGLCYDAASLPASISASASYEPSAAGWP
KADGLVSVLEGGTSTQRAIALEYKRPQEGIHGLLTAIGQAHGYLHKGYSG
AAIVIPGRYSSHPTPAEYVRDVLNAISGSRAIAVFSYSPPDTTSPTPFAG
RIQCVRPLVFDVHLRPANQGPKTQWVHMREGSTTRDAFFRFLQVAKRLSA
DPTAPRPTLRSELVAAIGRLAPGRDPIEYITNTADNKFLTKVWQFFWLEW
LATPAVLTPWKLEAGVYSAPGARTRILREDGTDFSQLWEGRVNSLKETIA
GMLNRGEISEAQGWEAFVGGISATGGGQDKQGVRARAHSYREDIDSALAQ
LRWIEDDGLPTDQGYRFMTICERYGGANSRAAIDYMGATLIQTGRYASFL
HYINRLSERKFAENPLAYTKPGPGGMPVFTEESYWEYLQDLETKLTDELR
VMRKVSGRARPRVRTTFQVELTLLRNYGFVSSTRHRLGVGIPIDWEQVVQ
ALNVDL

Ligand information

>8epx Chain L (length=23) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cttcccacctgcgccacgcgagg

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8epx Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI.
Resolution	3.15 Å
Binding residue (original residue number in PDB)	W50 E184 D284 Q290 W292 R295 D333 Q335 R340 S343 E435 W439 V459 S460 R462 T476 R488
Binding residue (residue number reindexed from 1)	W49 E180 D280 Q286 W288 R291 D329 Q331 R336 S339 E431 W435 V455 S456 R458 T472 R484

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:8epx, PDBe:8epx, PDBj:8epx
PDBsum	8epx
PubMed	36987874
UniProt	A0A2N8KYF9

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