Structure of PDB 8dt6 Chain D Binding Site BS02

Receptor Information

>8dt6 Chain D (length=371) Species: 1338011 (Elizabethkingia anophelis NUHP1)

MKFIVASGELQKALQTVSGVISGSQSRPILENFLFELENDNLKITASDGE
TTLITSIPVKSENNGRMAVPAKMFLDVIKSFGDQPLTFVEKEGSLLEILD
EKDNYFVALDNAEDYPELPEFDASKSVKIQAGILSEALVNTLFATSNDSL
RPVMTGVLFQFNENEANFVSTDSHRLVVYNRKDVMNVDNIEFIMPKKPLA
IIKNILSNTDDEVLIEFNENMAKFSFQDNIWICRLIDGKYPNYTAVIPKE
NPNVLTINRNLLLSSIRRASIFSNKSTNQVRFKLSGNLLHLHAEDTEYAN
KADMQIPCEYNGEDINIGFSSKFLTEMLSVLGSDDITMKMSQPNRPGIIE
PVDGLEENESILMLSMPVIGL

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 8dt6 Chain D Residue 403

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8dt6 Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis
• Resolution: 2.35 Å
• Binding residue (original residue number in PDB): E168 N194
• Binding residue (residue number reindexed from 1): E163 N189
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003887 DNA-directed DNA polymerase activity
• GO:0008408 3'-5' exonuclease activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006260 DNA replication
• GO:0006271 DNA strand elongation involved in DNA replication
• GO:0071897 DNA biosynthetic process

Cellular Component

• GO:0005737 cytoplasm
• GO:0009360 DNA polymerase III complex

External links

• PDB: RCSB:8dt6, PDBe:8dt6, PDBj:8dt6
• PDBsum: 8dt6
• UniProt: A0A077EHW1