Structure of PDB 8bet Chain D Binding Site BS02

Receptor Information
>8bet Chain D (length=524) Species: 86832 (Rhodotorula dairenensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CAPTSLPASATELPTTVPTGTVITGDYTGSYRPQVHYSPPKGFMNAPNGC
HRDRNGTYHLYYQYNPLEYVAGNQHWGHATSDDLYHWTNQPIAIFPPNST
SQVFSGSAVLDPNNTSGFFPNTTDGVVAVYTLNTPTLQVQEVAYSTDGGY
NFTPYENNPVLSVGSNQFRDPKVFWYEDHWVMAVAAANDFTIEIYTSPNL
TSWTFASNFTHHGLLGLAYECPNLVQVPFQDDPSKSAWLMYISINPGAPL
GGSVGQYFPGDFNGTHFVAYDSAARIADFAKDNYASQWFADTENGESISI
AWASNWQYTQQVPTSAQAFRSAMSLPRRNYLTNITRLGWDLVSLPYDLSP
VVGPSLLSSSEANSTADVDFTNVTSNAVWFSLNVTLPDAAIQNASLISAD
ASINITFLPSTKCSSDSPAATLTYFYAGLTNGALALTRPAASSSWGAENP
FFTDKFSYTLVDPLTSLVGVFDRSMLEVFVNEGAHSATMLVFPDSPVGSM
KVATGGLPEGTQVNLQVNGLESTW
Ligand information
Ligand IDFRU
InChIInChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
InChIKeyRFSUNEUAIZKAJO-ARQDHWQXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OC1C(O)C(OC1(O)CO)CO
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O
CACTVS 3.341OC[CH]1O[C](O)(CO)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)(CO)O)O)O)O
CACTVS 3.341OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
FormulaC6 H12 O6
Namebeta-D-fructofuranose;
beta-D-fructose;
D-fructose;
fructose
ChEMBLCHEMBL604608
DrugBank
ZINCZINC000001529270
PDB chain8bet Chain O Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8bet Insights into the Structure of the Highly Glycosylated Ffase from Rhodotorula dairenensis Enhance Its Biotechnological Potential.
Resolution2.38 Å
Binding residue
(original residue number in PDB)		N187 Q205 F246 S247 R311 D312 E362 Y426
Binding residue
(residue number reindexed from 1)		N45 Q63 F104 S105 R169 D170 E220 Y284
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.26: beta-fructofuranosidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8bet, PDBe:8bet, PDBj:8bet
PDBsum8bet
PubMed36499311
UniProtA0A856TAI5

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