Structure of PDB 8b4h Chain D Binding Site BS02

Receptor Information
>8b4h Chain D (length=362) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MITRGEFFMIKEMYERGMSISDIARELGIDRKTVRKYIHSPNPPSKSKRK
QRKSKLDPFKPYLQKRMLEDGVFNSEKLFFEIRQQGYTGGKTILKDYMKP
FRETAKKKYTVRYETLPGEQMQVDWKEVGEVVIEGKKVKLSLFVATLGYS
RMKYAVFTTSQDQEHLMECLIQSFKYFGGVPKKVLFDNMKTVTDGREQGV
VKWNQRFSEFASYYGFIPKVCRRAIQYIMDHFYVGTAFESIEELNFLLHR
WLDQVANRKPNATTGISPQERWAEESLKPLPLKDYDTSYLSYRKVHWDGS
FSYKGEQWLLSAEYAGKEILVKERLNGDIRLYFRGEEISHVDQQKKVISF
AEKIKKKQTEMA
Ligand information
>8b4h Chain H (length=55) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccttctggggaattttaaaccggcgattttggggaaaaaataatcggcct
tgaca
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8b4h IS21 family transposase cleaved donor complex traps two right-handed superhelical crossings.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		R31 K32 R35 R49 R52 S54 K55 G89 G90 T92 I93 R304 K305 H307 S313 Y314 K315
Binding residue
(residue number reindexed from 1)		R31 K32 R35 R49 R52 S54 K55 G89 G90 T92 I93 R293 K294 H296 S302 Y303 K304
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000150 DNA strand exchange activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0032196 transposition

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8b4h, PDBe:8b4h, PDBj:8b4h
PDBsum8b4h
PubMed37087515
UniProtQ45618|TRA6_GEOSE Putative transposase for insertion sequence element IS5376

[Back to BioLiP]