Structure of PDB 8a4b Chain D Binding Site BS02

Receptor Information
>8a4b Chain D (length=169) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHE
KRVKLQIWDTAGLERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWAT
QIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKE
NISVRQAFERLVDAICDKM
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8a4b Chain D Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a4b Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T36 T54
Binding residue
(residue number reindexed from 1)		T18 T36
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:8a4b, PDBe:8a4b, PDBj:8a4b
PDBsum8a4b
PubMed35871249
UniProtP20337|RAB3B_HUMAN Ras-related protein Rab-3B (Gene Name=RAB3B)

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