Structure of PDB 7zdu Chain D Binding Site BS02

Receptor Information
>7zdu Chain D (length=585) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQH
MIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQ
VLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVP
LLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARL
SGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSG
ILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFF
QPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIE
AEELFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLS
YQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDAS
EQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALL
NPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWD
VIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7zdu Chain D Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zdu Occ(apo/return) conformation of CydDC mutant (E500Q.C) in ATP(CydC)/ATP(CydD) bound state (Dataset-19)
Resolution2.98 Å
Binding residue
(original residue number in PDB)		S390 Q430
Binding residue
(residue number reindexed from 1)		S389 Q429
Annotation score1
Enzymatic activity
Enzyme Commision number 7.4.2.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015439 ABC-type heme transporter activity
GO:0016887 ATP hydrolysis activity
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006865 amino acid transport
GO:0006869 lipid transport
GO:0033228 cysteine export across plasma membrane
GO:0034775 glutathione transmembrane transport
GO:0035351 heme transmembrane transport
GO:0042883 cysteine transport
GO:0045454 cell redox homeostasis
GO:0055085 transmembrane transport
GO:1903605 cytochrome biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055051 ATP-binding cassette (ABC) transporter complex, integrated substrate binding

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zdu, PDBe:7zdu, PDBj:7zdu
PDBsum7zdu
PubMed37095238
UniProtP29018|CYDD_ECOLI Glutathione/L-cysteine transport system ATP-binding/permease protein CydD (Gene Name=cydD)

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