Structure of PDB 7ye2 Chain D Binding Site BS02

Receptor Information
>7ye2 Chain D (length=1140) Species: 565050 (Caulobacter vibrioides NA1000) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFDQIRISLASPEKIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPT
KDYECLCGKYKRMKYKGIICEKCGVEVTLARVRRERMGHIELASPVAHIW
FLKSLPSRIAMMLDMPLKDIERVLYFEYYIVTEPGPLKQHQLLSEDDYMR
AQEEYGDDSFTAEIGAEAIQNLLKAIDLEKEAERLREELSGTVSDMKQKK
FSKRLKILEAFQESGNRPEWMVLTVVPVIPPELRPLVPLDGGRFATSDLN
DLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVI
TGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHEC
GLPKKMALELFKPFIYARLDAKGLSGTVKQSKRMVEREQPQVWDILEEVI
REHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQM
AVHVPLSLEAQLEARVLMMSTNNILSPANGRPIIVPSQDIVLGLYYLSVA
RDGEPGEGKIFADLGEIEAAMDAGVVSLHAKIKARHTEMTPEGVLLRKVI
DTTPGRMKIAALLPHHPQIGHRLIEKALTKKEIGNLIDIVYRHCGQKATV
IFADKVMGLGFKEAAKAGISFGKDDIIIPVRKTAIVEETRKLAEEYEQQY
ITKGEKYNKVVDAWAKATDRVADEMMAELQMKHKDENGREKEINAIYMMA
HSGARGSQAQMKQLGGMRGLMAKPSGEIIETPIVSNFKEGLTVQEYFNST
HGARKGLADTALKTANSGYLTRRLVDVAQDCIIVEEDCGTTKGITLRAVV
EGGDVLVSLGSRVLGRFTAEDVKDPGTGELVVPADTYIDENIADAIEAAV
VQSVKVRSVLTCEAKIGVCGACYGRDLARGTPVNIGEAVGVIAAQSIGEP
GTQLTITGGLPRVAELFEARRPKDCAVIAEMDGRVEFGKDYKNKRRIKIT
PDKHIAVHDGDYITKGEYIIDGNPDPHDILRILGVEALANFLVDEIQEVY
RLQGVPINDKHIETIVRQMLQKVEILEPGDTGLIKGDHLDKPEFDKEQEK
AIARPAVTQPVLLGITKASLQTKSFISAASFQETTRVLTEASVHGKTDTL
EGLKENVIVGRLIPAGTGSYLRSLQRVAAKRDEQLAQQRE
Ligand information
>7ye2 Chain I (length=68) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgtcgcgactcagcgactcttaatcgaaggttaacacgatgtttcccgcc
tgtcaaggggctaagggc
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ye2 Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA
Resolution3.8 Å
Binding residue
(original residue number in PDB)
L121 D213 R261 A321 K334 K336 R354 A428 P429 T786 G790 R794 R1165 E1323
Binding residue
(residue number reindexed from 1)
L105 D195 R243 A303 K316 K318 R336 A410 P411 T764 G768 R772 R946 E1083
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ye2, PDBe:7ye2, PDBj:7ye2
PDBsum7ye2
PubMed
UniProtA0A0H3C4W8

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