Structure of PDB 7uin Chain D Binding Site BS02

Receptor Information
>7uin Chain D (length=387) Species: 39491 (Agathobacter rectalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLMEQILSSDNLNRAYLQVVRNKGAEGVDGMKYTELKEHLAKNGETIKGQ
LRTRKYKPQPGVPTVTDRFIQQAIAQVLTPIYEEQFHDHSYGFRPNRCAQ
QAILTALNIMNDGNDWIVDIDLEKFFDTVNHDKLMTLIGRTIKDGDVISI
VRKYLVSGGNLSPLLANIMLNELDKEMEKRGLNFVRYADDCIIMVGSEMS
ANRVMRNISRFIEEKLGLKVNMTKSKVDRPSGLKYLGFGFYFDPRAHQFK
AKPHAKSVAKFKKRMKELTCRSWGVSNSYKVEKLNQLIRGWINYFKIGSM
KTLCKELDSRIRYRLRMCIWKQWKTPQNQEKNLVKLGIDRNTARRVAYTG
KRIAYVCNKGAVNVAISNKRLASFGLISMLDYYIEKC
Ligand information
Receptor-Ligand Complex Structure
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PDB7uin Structures of a mobile intron retroelement poised to attack its structured DNA target
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R266 S268 Y278 F279 P281 R282 A283 F286 K289 S336 K338 T339 S346 R347 R349 Y350 K361 N378 R381 R382 V383 Y385 T386 R389 Y392 V393 K396 G397 A398 N400 S404 N405
Binding residue
(residue number reindexed from 1)		R229 S231 Y241 F242 P244 R245 A246 F249 K252 S299 K301 T302 S309 R310 R312 Y313 K324 N341 R344 R345 V346 Y348 T349 R352 Y355 V356 K359 G360 A361 N363 S367 N368
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003964 RNA-directed DNA polymerase activity
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0006974 DNA damage response

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Molecular Function
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Biological Process
External links
PDB RCSB:7uin, PDBe:7uin, PDBj:7uin
PDBsum7uin
PubMed36356138
UniProtA0A173ZME3

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