Structure of PDB 7syw Chain D Binding Site BS02

Receptor Information

>7syw Chain D (length=221) Species: 9986 (Oryctolagus cuniculus)

KEWLPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVL
KIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIIL
AKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSA
PVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWK
ETVFTKSPYQEFTDHLVKTHT

Ligand information

>7syw Chain z (length=188)

cccccccucccgggagagccauaguggucugcggaaccggugaguacacc
ggaaugauuugggcgugcccccgcaagacugcuagccgaguaguguuggg
ucgcgaaaggccuugugguacugccugauagggugcuugcgagugccccg
ggaggucucguagaccgugcaccaugagcacgaauccu

.....<<<<<<<<<<<.<<<<<<<<<<<<<<<<<..<<<<<<....>>>>
>><<<.>>>.<<<....>>>>>>>>.>>>>>>>><<<.....<<......
..>>....>>>....>>>>.>><<<<....>>>><<...((((.>>>>>>
>>>>>.))))............................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7syw Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): P111 F124 V147 I151
• Binding residue (residue number reindexed from 1): P54 F67 V90 I94

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit

External links

• PDB: RCSB:7syw, PDBe:7syw, PDBj:7syw
• PDBsum: 7syw
• PubMed: 35822879
• UniProt: G1SV32|RL7_RABIT Large ribosomal subunit protein uL30 (Gene Name=RPL7)