Structure of PDB 7qwr Chain D Binding Site BS02

Receptor Information
>7qwr Chain D (length=292) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMI
VRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTG
LLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLAR
TTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQ
NVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPV
YEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERA
Ligand information
>7qwr Chain 7 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu
<<<<<<<<<....<<<<<<<<.....<<<<<<............>>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB7qwr Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K10 F13 K14 Y16 V18 F20 R22 R24 T28 Y30 R33 R50 I52 R54 T56 N57 R58 I61 Q63 E70 D72 M73 I74 Y79 N94 R152 T155 G156 N157 K158 H198 N203 V204 Y207 Q222 F223 Y226 Y253 K255 K256 K258 R259 E260 V261 K262 K263 W266 N267 K270 M271 L273 K276 K277 R279 V280 K284
Binding residue
(residue number reindexed from 1)		K8 F11 K12 Y14 V16 F18 R20 R22 T26 Y28 R31 R48 I50 R52 T54 N55 R56 I59 Q61 E68 D70 M71 I72 Y77 N92 R150 T153 G154 N155 K156 H196 N201 V202 Y205 Q220 F221 Y224 Y251 K253 K254 K256 R257 E258 V259 K260 K261 W264 N265 K268 M269 L271 K274 K275 R277 V278 K282
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qwr, PDBe:7qwr, PDBj:7qwr
PDBsum7qwr
PubMed35201867
UniProtP19949|RL5_RABIT Large ribosomal subunit protein uL18 (Gene Name=RPL5)

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