Structure of PDB 7qpr Chain D Binding Site BS02

Receptor Information
>7qpr Chain D (length=689) Species: 470 (Acinetobacter baumannii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPGEEVSQAKQQLKLIIDPYLSVSEVEKVLAACDFGDLAHTGITRKSGEP
YILHPIAVSCILANMRLDPETLMAALLHDVIEDTQYTKDDIIERFGQTVA
ELVDGVTKLSQSSDKEYNKAASFRKILQATLQDPRVIIIKLADRYHNMTT
LGALRPDKRARIAQETFDIFVPMARLVGMNEMADNLENLCYQNLDLDMFD
NVQNALLQTKPERCKYQSIWEQNLAELLHNYHIQGRIKKKNNNIELLRHF
VKNEMDLQELTHSHAFEIVLQSIADCDRLVAALKENFQVIQYQDHIRRPL
PGGNQSLMIKLKGEKTTLSLTIQTELMRKAARFGVVLGENAPQTCRSAIQ
ASMQNLNTLIDTFNDLLDYLHQEKIWVYTPHGQLHELPQGATVVDFAYSA
SLFLGNHAVGAKVDGEIKPLSTPLVSGQVIEIITDVLATPNPDWLSFINT
QKARRALQHVLKDQDIEEQRLVGAQALSRALKLFNRSINDLSDADWLDLL
QWRHIDNKDALFEQIAVGDLLPQLVANHLFANDKHPRAENSDRLIQGTEG
IDVKYAHCCNPILGDPIQGHLTRRGLIVHRIRCHNLLHEQHLHPENIMPL
QWKADDVDDVRFTAYLAIYMAMNDEQVSDLIYQCRKNNAGVEMVHSNEQR
TFVNIVVNNRKHIAKVIRDLRMHYGFPRIERLDAPAPQM
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7qpr Chain D Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qpr Structure of full length SpoT
Resolution2.513 Å
Binding residue
(original residue number in PDB)		C565 H585 C589
Binding residue
(residue number reindexed from 1)		C559 H579 C583
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.6.5: GTP diphosphokinase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008728 GTP diphosphokinase activity
GO:0008893 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity
GO:0016301 kinase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0015969 guanosine tetraphosphate metabolic process
GO:0015970 guanosine tetraphosphate biosynthetic process
GO:0016310 phosphorylation
GO:0042594 response to starvation
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qpr, PDBe:7qpr, PDBj:7qpr
PDBsum7qpr
PubMed
UniProtV5V8V7

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