Structure of PDB 7pmq Chain D Binding Site BS02

Receptor Information
>7pmq Chain D (length=455) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSG
KTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVM
DEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDP
LAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKK
DCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAA
RGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEAQR
ANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGDVLG
ALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCR
VRLLK
Ligand information
>7pmq Chain H (length=42) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaaggguuucgacccuucccaauauggcuguucgccauuu
<<<<<<<<<....>>>>>>>>><<.<<<<<.....>>>>>>>
Receptor-Ligand Complex Structure
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PDB7pmq Structural basis for RNA-duplex unwinding by the DEAD-box helicase DbpA.
Resolution3.22 Å
Binding residue
(original residue number in PDB)		P79 T80 R81 G108 P111 G113 T129 G131 R132 R157 G162 F163 N249 T250 K251 H272 G273 R278 R280 T298 D299 V300 W320
Binding residue
(residue number reindexed from 1)		P77 T78 R79 G106 P109 G111 T127 G129 R130 R155 G160 F161 N247 T248 K249 H270 G271 R276 R278 T296 D297 V298 W318
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0033677 DNA/RNA helicase activity
GO:0034458 3'-5' RNA helicase activity
GO:0043531 ADP binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pmq, PDBe:7pmq, PDBj:7pmq
PDBsum7pmq
PubMed37221012
UniProtP21693|DBPA_ECOLI ATP-dependent RNA helicase DbpA (Gene Name=dbpA)

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