Structure of PDB 7obr Chain D Binding Site BS02

Receptor Information
>7obr Chain D (length=292) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMI
VRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTG
LLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLAR
TTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQ
NVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPV
YEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERA
Ligand information
>7obr Chain 7 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu
<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7obr Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		K8 K10 F13 K14 V18 F20 R21 R22 R24 T28 Y30 R33 R50 I52 R54 T56 N57 R58 I61 I69 D72 M73 I74 Y79 N94 R152 T155 G156 N157 K158 N203 V204 Y207 Q222 Q225 Y226 Y253 K255 K258 E260 V261 K263 R265 W266 N267 R268 K270 M271 L273 K276 V280
Binding residue
(residue number reindexed from 1)		K6 K8 F11 K12 V16 F18 R19 R20 R22 T26 Y28 R31 R48 I50 R52 T54 N55 R56 I59 I67 D70 M71 I72 Y77 N92 R150 T153 G154 N155 K156 N201 V202 Y205 Q220 Q223 Y224 Y251 K253 K256 E258 V259 K261 R263 W264 N265 R266 K268 M269 L271 K274 V278
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7obr, PDBe:7obr, PDBj:7obr
PDBsum7obr
PubMed34260909
UniProtP19949|RL5_RABIT Large ribosomal subunit protein uL18 (Gene Name=RPL5)

[Back to BioLiP]