Structure of PDB 7n86 Chain D Binding Site BS02

Receptor Information
>7n86 Chain D (length=210) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVAPKFLANMTSVILPEDLPVGAQAFWLVAEDQDNDPLTYGMSGPNAYFF
AVTPKTGEVKLASALDYETLYTFKVTISVSDPYIQVQREMLVIVEDRNDN
APVFFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSE
HLFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLP
VFLSISVVDQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7n86 Chain D Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7n86 Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.
Resolution3.175 Å
Binding residue
(original residue number in PDB)		E17 D66 E68 D99
Binding residue
(residue number reindexed from 1)		E17 D66 E68 D99
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7n86, PDBe:7n86, PDBj:7n86
PDBsum7n86
PubMed34871294
UniProtQ9BYE9|CDHR2_HUMAN Cadherin-related family member 2 (Gene Name=CDHR2)

[Back to BioLiP]