Structure of PDB 7n27 Chain D Binding Site BS02

Receptor Information

>7n27 Chain D (length=57) Species: 9606 (Homo sapiens)

GEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYI
HDFNRRH

Ligand information

>7n27 Chain J (length=6) Species: 32630 (synthetic construct)

cFAFKA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7n27 Crystal Structure of chromodomain of CDYL in complex with inhibitor UNC6261
• Resolution: 1.85 Å
• Binding residue (original residue number in PDB): L60 Y61 E62 V63 W83 Y86 E94 H98 L99 V100 N101 C102 Y105
• Binding residue (residue number reindexed from 1): L4 Y5 E6 V7 W27 Y30 E38 H42 L43 V44 N45 C46 Y49

Enzymatic activity

• Enzyme Commision number: 4.2.1.-

External links

• PDB: RCSB:7n27, PDBe:7n27, PDBj:7n27
• PDBsum: 7n27
• UniProt: Q9Y232|CDYL_HUMAN Chromodomain Y-like protein (Gene Name=CDYL)