Structure of PDB 7lo5 Chain D Binding Site BS02

Receptor Information
>7lo5 Chain D (length=1012) Species: 980427 (Deinococcus wulumuqiensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLQLVKKFQKRLEDIVAYGGTRNESSVRAAFQQLLSDWAEGSGLRLITE
VTQKAVAGNNVRPDGTLKDSLQQSRGYWESKDEADTLDDEIQKKLAKGYP
RDNIIFEDSRLAVLMQNGEEVQRVDMGDAGALAGLLKLFFEFEPPQVLEF
RKAVDHFKDEMPHLLKILREAADAAEQKADYRGERDHFVEIAKEAINPDF
SPRDAREMLIQHILTGDLFTSVFDNAQYHEDNNIAQQLQQLAATFYKGPV
KRDIAERTKRYYGAIQAAAAQIADHHEKQRFLKALYENFYRAYNPAGAER
LGIFYTPGEIVRFMIEATDTLLEKHFQKELADKGVEILDPATGTGTFITE
LIDFLPKAKLEQKYREELHCNELALLPYYIANLNIEATYAQKMGRYEEFR
NIVLVDTLDNTSGLFGSVTAENLERAKRQNARPVRVIIGNPPYRANQANE
NDNNKNREYKEIDRRIKATYVAASTAQKTKLYDMYSRFLRWATDRLKEDG
IVAFVSNSSFIDSRTFDGFRKEVVKDFDHIYILDMKGNANTSGERRKREG
GNVFNDQIKVGVAVYFLVRSAKDTKIWYHAVPDFWRAREKLEWLKTTKFE
DIEFDHIRPDAKHNWLGQVDEENDWNEFLPVADKDTKQAKGLGQERAIFK
LYSLGVVTNRDEWVYSRAEDELADKVRYFIGRYNEIIKLPLGDLMSRNWE
GDIKMTRATIADAQSRKSYSLEKNSIVPSLYRPFDVLKMYFSKNLNEMQY
QMPSIFPKGVGENVVIALSGSPAAKPFQVLATDILPSLDLLEKTQCLPFY
RYTMNGERLNNITDYALKAFQTHYAISREDIFHYVYAVLHHPAYREKYAL
NLRQEFPRIPFYPEFGRWAAWGRELMALHIGFESVAPYPLKRTDEPPKND
TPEALALAKKARLKVQRDAAKQPTGAVELDGLTTLAGIPAAAWAYKLGNR
SALEWVLERHKETTPKDATIREKFNTYRFADHKERVIDLLARVTTVSVET
VRIVGEMPAETM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lo5 Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		N24 E25 S26 N59 V61 R62 K97 Y99
Binding residue
(residue number reindexed from 1)		N24 E25 S26 N59 V61 R62 K97 Y99
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7lo5, PDBe:7lo5, PDBj:7lo5
PDBsum7lo5
PubMed33826880
UniProtA0A345IJ72

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