Structure of PDB 7kq8 Chain D Binding Site BS02

Receptor Information
>7kq8 Chain D (length=294) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYT
YCGSCAAHAYKQVDPSITRRIFILGPSHHVPLSRCALSSVDIYRTPLYDL
RIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTI
IPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYD
ESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLL
NAITELQKNGMNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain7kq8 Chain D Residue 312 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7kq8 MEMO1 is an Iron Containing Regulator of Metal Homeostasis in the Cell
Resolution2.15 Å
Binding residue
(original residue number in PDB)		H49 H81 C244
Binding residue
(residue number reindexed from 1)		H46 H78 C241
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0032886 regulation of microtubule-based process
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7kq8, PDBe:7kq8, PDBj:7kq8
PDBsum7kq8
PubMed38640016
UniProtQ9Y316|MEMO1_HUMAN Protein MEMO1 (Gene Name=MEMO1)

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