Structure of PDB 7bjv Chain D Binding Site BS02

Receptor Information
>7bjv Chain D (length=240) Species: 7102 (Heliothis virescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVPPLTANQKSLIARLVYYQEGYEQPSEEDLKRVTQTWDSDMPFRQITEM
TILTVQLIVEFAKGLPGFSKISQSDQITLLKACSSEVMMLRVARRYDAAT
DSVLFANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYSMMMDNVHYALLTA
IVIFSDRPGLEQPSLVEEIQRYYLNTLRVYILNQNSASPRSAVIFGKILG
ILTEIRTLGMQNSNMCISLKLKNRKLPPFLEEIWDVADVA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7bjv Chain D Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7bjv Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP.
Resolution3.05 Å
Binding residue
(original residue number in PDB)		Y304 G356
Binding residue
(residue number reindexed from 1)		Y19 G64
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0035100 ecdysone binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0035076 ecdysone receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bjv, PDBe:7bjv, PDBj:7bjv
PDBsum7bjv
PubMed33746550
UniProtO18473|ECR_HELVI Ecdysone receptor (Gene Name=EcR)

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