Structure of PDB 6yy3 Chain D Binding Site BS02

Receptor Information
>6yy3 Chain D (length=515) Species: 595536 (Methylosinus trichosporium OB3b) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DALKVNRAPVGVEPQEVHKWLQSFNWDFKENRTKYPTKYHMANETKEQFK
VIAKEYARMEAAKDERQFGTLLDGLTRLGAGNKVHPRWGETMKVISNFLE
VGEYNAIAASAMLWDSATAAEQKNGYLAQVLDEIRHTHQCAFINHYYSKH
YHDPAGHNDARRTRAIGPLWKGMKRVFADGFISGDAVECSVNLQLVGEAC
FTNPLIVAVTEWASANGDEITPTVFLSVETDELRHMANGYQTVVSIANDP
ASAKFLNTDLNNAFWTQQKYFTPVLGYLFEYGSKFKVEPWVKTWNRWVYE
DWGGIWIGRLGKYGVESPASLRDAKRDAYWAHHDLALAAYAMWPLGFARL
ALPDEEDQAWFEANYPGWADHYGKIFNEWKKLGYEDPKSGFIPYQWLLAN
GHDVYIDRVSQVPFIPSLAKGTGSLRVHEFNGKKHSLTDDWGERQWLIEP
ERYECHNVFEQYEGRELSEVIAEGHGVRSDGKTLIAQPHTRGDNLWTLED
IKRAGCVFPDPLAKF
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain6yy3 Chain D Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6yy3 High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E144 E209 E243 H246
Binding residue
(residue number reindexed from 1)		E133 E198 E232 H235
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E114 E144 H147 E209 E243 H246
Catalytic site (residue number reindexed from 1) E103 E133 H136 E198 E232 H235
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6yy3, PDBe:6yy3, PDBj:6yy3
PDBsum6yy3
PubMed
UniProtP27353|MEMA_METTR Methane monooxygenase component A alpha chain (Gene Name=mmoX)

[Back to BioLiP]