Structure of PDB 6xnx Chain D Binding Site BS02

Receptor Information
>6xnx Chain D (length=343) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MALQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDI
KQNHLKLKPAIFSKDSCYLPPLRYPATCSYKKHQYIIHGGKTPNNELSDK
IYIMSVACKNNKKVTFRCTEKDLVGDVPEPRYGHSIDVVYSRGKSMGVLF
GGRSYMPSTQRTTEKWNSVADCLPHVFLIDFEFGCATSYILPELQDGLSF
HVSIARNDTVYILGGHSLASNIRPANLYRIRVDLPLGTPAVNCTVLPGGI
SVSSAILTQTNNDEFVIVGGYQLENQKRMVCSLVSLGDNTIEISEMETPD
WTSDIKHSKIWFGSNMGNGTIFLGIPGDNKMSEAFYFYTLRCS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6xnx Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
K58 N117 K119
Binding residue
(residue number reindexed from 1)
K58 N111 K113
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6xnx, PDBe:6xnx, PDBj:6xnx
PDBsum6xnx
PubMed32945578
UniProtP21784|RAG2_MOUSE V(D)J recombination-activating protein 2 (Gene Name=Rag2)

[Back to BioLiP]