Structure of PDB 6oqq Chain D Binding Site BS02

Receptor Information
>6oqq Chain D (length=131) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMN
EIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAA
ELKHVLTSIGEKLTDAEVDDMNIQQFAALLS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6oqq Chain D Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6oqq Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases.
Resolution2.102 Å
Binding residue
(original residue number in PDB)		D94 N96 D98 L100
Binding residue
(residue number reindexed from 1)		D90 N92 D94 L96
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030234 enzyme regulator activity
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
GO:0051019 mitogen-activated protein kinase binding
Biological Process
GO:0000742 karyogamy involved in conjugation with cellular fusion
GO:0006606 protein import into nucleus
GO:0006661 phosphatidylinositol biosynthetic process
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0007010 cytoskeleton organization
GO:0007114 cell budding
GO:0010968 regulation of microtubule nucleation
GO:0016237 microautophagy
GO:0030050 vesicle transport along actin filament
GO:0042144 vacuole fusion, non-autophagic
GO:0051300 spindle pole body organization
GO:0071474 cellular hyperosmotic response
GO:1903525 regulation of membrane tubulation
GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation
Cellular Component
GO:0000131 incipient cellular bud site
GO:0005737 cytoplasm
GO:0005816 spindle pole body
GO:0005823 central plaque of spindle pole body
GO:0005856 cytoskeleton
GO:0005933 cellular bud
GO:0005934 cellular bud tip
GO:0005935 cellular bud neck
GO:0030479 actin cortical patch
GO:0031475 myosin V complex
GO:0043332 mating projection tip
GO:0045160 myosin I complex
GO:0051286 cell tip

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6oqq, PDBe:6oqq, PDBj:6oqq
PDBsum6oqq
PubMed31123136
UniProtP06787|CALM_YEAST Calmodulin (Gene Name=CMD1)

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