Structure of PDB 6oig Chain D Binding Site BS02

Receptor Information
>6oig Chain D (length=296) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRL
VVRFTNKDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYAT
GLLIARRTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQ
RTTTGARVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFG
GHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRADP
AFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Ligand information
>6oig Chain 7 (length=121) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguugcggccauaucuaccagaaagcaccguuucccguccgaucaacugu
aguuaagcugguaagagccugaccgaguaguguagugggugaccauacgc
gaaacucaggugcugcaaucu
<<<<<<<<.....<<<<<<<<.....<..<<..............>>...
..>....>>>>>>.>>.<<<<<.......<<.<<..<<....>>.>>.>>
.....>>>>>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB6oig An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		A262 F263 S270 S273 S274 T278 P279 F280 R281 R282 R284 K287 T288 Y290 R293 R314 T316 N317 K318 Q323 T328 I329 T330 G331 D332 V333 V334 Y339 H350 N354 R412 T414 T415 G416 A417 R418 Y458 Y467 E470 E481 L482 F483 T516 K518 F520 K522 Q524 Y525 A526 E528 S529 K530 Y532 R533 Q534 T535 K536 L537 K539 R542 R545 K549
Binding residue
(residue number reindexed from 1)		A1 F2 S9 S12 S13 T17 P18 F19 R20 R21 R23 K26 T27 Y29 R32 R53 T55 N56 K57 Q62 T67 I68 T69 G70 D71 V72 V73 Y78 H89 N93 R151 T153 T154 G155 A156 R157 Y197 Y206 E209 E220 L221 F222 T255 K257 F259 K261 Q263 Y264 A265 E267 S268 K269 Y271 R272 Q273 T274 K275 L276 K278 R281 R284 K288
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6oig, PDBe:6oig, PDBj:6oig
PDBsum6oig
PubMed33219089
UniProtP26321|RL5_YEAST Large ribosomal subunit protein uL18 (Gene Name=RPL5)

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