Structure of PDB 6n7e Chain D Binding Site BS02

Receptor Information
>6n7e Chain D (length=319) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTR
IPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTK
LDAMLEEFKKGKSHLAIVQFYEVLGIVTLEDVIEEIIKSEILDETDLYTD
NRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFS
PSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLIL
QGKVEVEAGKEGMKFEASAFSYYGVMALTASPVLLQVYIPDYSVRALSDL
QFVKISRQQYQNALMLEHH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6n7e Chain D Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6n7e Mg2+-ATP Sensing in CNNM, a Putative Magnesium Transporter.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		E570 E584
Binding residue
(residue number reindexed from 1)		E130 E144
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0010960 magnesium ion homeostasis

View graph for
Biological Process
External links
PDB RCSB:6n7e, PDBe:6n7e, PDBj:6n7e
PDBsum6n7e
PubMed31864811
UniProtQ9H8M5|CNNM2_HUMAN Metal transporter CNNM2 (Gene Name=CNNM2)

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