Structure of PDB 6kdb Chain D Binding Site BS02

Receptor Information
>6kdb Chain D (length=284) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHE
GNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTG
RLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPV
MIDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLK
KVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTELERIFGFPVHYTDVS
NMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6kdb Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Resolution2.862 Å
Binding residue
(original residue number in PDB)		N656 P659 M702 S778
Binding residue
(residue number reindexed from 1)		N87 P90 M133 S209
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:6kdb, PDBe:6kdb, PDBj:6kdb
PDBsum6kdb
PubMed32083663
UniProtQ9UBC3|DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Gene Name=DNMT3B)

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