Structure of PDB 6jxd Chain D Binding Site BS02
Receptor Information
>6jxd Chain D (length=97) Species:
9606
(Homo sapiens) [
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RKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEAS
RLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>6jxd Chain J (length=147) [
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catatatgccggtctcacacgtgcctggagactagtaagcgcttctagtg
gcggttaaaacgcggtagacagcgcgtacgtgcgtttaagcggtgctaga
gctgtctacgaccaattgagcggcctcggcaccgggatatatggtac
Receptor-Ligand Complex Structure
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PDB
6jxd
PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
R26 K27 R28 R30 K31 Y37
Binding residue
(residue number reindexed from 1)
R1 K2 R3 R5 K6 Y12
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0030527
structural constituent of chromatin
GO:0046982
protein heterodimerization activity
Cellular Component
GO:0000786
nucleosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:6jxd
,
PDBe:6jxd
,
PDBj:6jxd
PDBsum
6jxd
PubMed
31848352
UniProt
P06899
|H2B1J_HUMAN Histone H2B type 1-J (Gene Name=H2BC11)
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