Structure of PDB 6jq0 Chain D Binding Site BS02

Receptor Information
>6jq0 Chain D (length=566) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSFESVGGLDNYINQLKEMVMLPLLYPEIFQRFNMQPPRGVLFHGPPGTG
KTLMARALAAACSSENKKVSFYMRKGADCLSKWVGEAERQLRLLFEEAKS
TQPSIIFFDQIDGLAPVRSSKQEQIHASIVSTLLALMDGMESRGQVIIIG
ATNRPDAVDPALRRPGRFDREFYFPLPDRDARKKIIEIHTRNWDPPVPEW
LCSMLAEKSKGYGGADLRALCTEAALNSIKRTYPQLYRSTKRLQIDPKTI
KVKVKDFVMSMKRMIPSSERSSISPSKPLSPELKPLLNEAFQDIEKTLQK
LMPVASKLNPLEEVMYDDPKENDFEYQQRLETFETLRIYKPRFLICGRKG
LGQTALGPAILQQYEGVHVQSFDMSTLLQDSTQSIETSIIHLFLEVRRHT
PSIIYIPDIDNWLNVLPLTAITTFSSMLERLDFSDQILFLALSSSPLSEL
HPQLREWFSSKQSVYSLQYPTRDSIIAFFQPILELIKASPTELPGGIPRK
RRVLPELPLALTPLKQLLIDSTTGFTVDQLLHLHSFLYQIIWNTKSEWNR
NSVVDECERAVKEFMI
Ligand information
Ligand IDATP
InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
FormulaC10 H16 N5 O13 P3
NameADENOSINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL14249
DrugBankDB00171
ZINCZINC000004261765
PDB chain6jq0 Chain E Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jq0 Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone.
Resolution3.54 Å
Binding residue
(original residue number in PDB)		R426 R429
Binding residue
(residue number reindexed from 1)		R164 R167
Annotation score5
Enzymatic activity
Enzyme Commision number 3.6.1.-
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042393 histone binding
GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity
Biological Process
GO:0006334 nucleosome assembly
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0045815 transcription initiation-coupled chromatin remodeling
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6jq0, PDBe:6jq0, PDBj:6jq0
PDBsum6jq0
PubMed31848341
UniProtO14114|ATD2_SCHPO ATPase histone chaperone abo1 (Gene Name=abo1)

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