Structure of PDB 6jil Chain D Binding Site BS02

Receptor Information

>6jil Chain D (length=298) Species: 1914 (Streptomyces lavendulae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MGILALVTDAVSLPIDYDMPPLLEACRTVGITAEVCDWEDGTVDWSRFEA
VVFRSPWTWAERQAEFLAFCERVSHVTRLITPMPLVRWALDKRYLADLAA
HGVPVIPTTVVAPGSDALAAVRDFLAARPEAREFVVKPTDGCYSKDVQRY
QRSLAEPASRHVARLLANGSHVILQPYVESVDRHGETDLTFFDGVYSHAI
HKGAMLMPDGTVHVPTLDFRQARDADEDQRAVAAAALAASVAHLGLDLPL
VCGRVDLVRGADGSPMVLEMELCEPSLNLTFSEDGALRFAQALAERLK

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6jil Chain D Residue 405 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6jil Cyclization mechanism catalyzed by an ATP-grasp enzyme essential for d-cycloserine biosynthesis.
Resolution	2.32 Å
Binding residue (original residue number in PDB)	C142 E269 E271
Binding residue (residue number reindexed from 1)	C142 E269 E271
Annotation score	1

Enzymatic activity

Enzyme Commision number

6.3.3.5: O-ureido-D-serine cyclo-ligase.

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0005524	ATP binding
GO:0016874	ligase activity
GO:0016882	cyclo-ligase activity
GO:0046872	metal ion binding

	Biological Process
GO:0017000	antibiotic biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:6jil, PDBe:6jil, PDBj:6jil
PDBsum	6jil
PubMed	31793174
UniProt	D2Z030\|DCSG_STRLA Cycloserine biosynthesis protein DcsG (Gene Name=dcsG)

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