Structure of PDB 6i5n Chain D Binding Site BS02
Receptor Information
>6i5n Chain D (length=151) Species:
9606
(Homo sapiens) [
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SMQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSD
YLLTISVKTSAGPTNLRIEYQDGKFRLDSILAAFDSVVHLIDYYVQMCKT
VHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQ
V
Ligand information
>6i5n Chain L (length=9) Species:
9606
(Homo sapiens) [
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PDYTSIHIV
Receptor-Ligand Complex Structure
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PDB
6i5n
Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
Resolution
1.98 Å
Binding residue
(original residue number in PDB)
Y128 M132 X133 V148 H149 L150
Binding residue
(residue number reindexed from 1)
Y93 M97 X98 V101 H102 L103
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0035556
intracellular signal transduction
View graph for
Biological Process
External links
PDB
RCSB:6i5n
,
PDBe:6i5n
,
PDBj:6i5n
PDBsum
6i5n
PubMed
31182716
UniProt
O14508
|SOCS2_HUMAN Suppressor of cytokine signaling 2 (Gene Name=SOCS2)
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