Structure of PDB 6hsd Chain D Binding Site BS02

Receptor Information
>6hsd Chain D (length=160) Species: 953739 (Streptomyces venezuelae ATCC 10712) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKLSGGVEWALHCCVVLTAASRPVPAARLAELHDVSPSYLAKQMQALSRA
GLVRSVQGKTGGYVLTRPAVEITLLDVVQAVDGPDPAFVCTEIRQRGPLA
TPPEKCTKACPIARAMGAAEAAWRASLAATTIADLVATVDDESGPDALPG
VGAWLIEGLG
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain6hsd Chain D Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6hsd Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe-2S] Cluster Coordinated by Cys, Glu, and His Residues.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		E8 H12
Binding residue
(residue number reindexed from 1)		E8 H12
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:6hsd, PDBe:6hsd, PDBj:6hsd
PDBsum6hsd
PubMed30657661
UniProtF2RGC9

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