Structure of PDB 6hc3 Chain D Binding Site BS02
Receptor Information
>6hc3 Chain D (length=192) Species:
9606
(Homo sapiens) [
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SSVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELP
DSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKA
MTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNL
SDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT
Ligand information
>6hc3 Chain F (length=22) [
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tttggtggaaattttttgttag
Receptor-Ligand Complex Structure
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PDB
6hc3
DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
S55 Y57 L58 S61 T78 I81 A85 W88 R89 Q100 Y103 W107 R140 K147 K156 R157 N163 F170 P178 L182
Binding residue
(residue number reindexed from 1)
S13 Y15 L16 S19 T36 I39 A43 W46 R47 Q58 Y61 W65 R98 K105 K114 R115 N121 F128 P136 L140
Binding affinity
PDBbind-CN
: Kd=13.6nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6hc3
,
PDBe:6hc3
,
PDBj:6hc3
PDBsum
6hc3
PubMed
31114891
UniProt
Q00059
|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)
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