Structure of PDB 6h77 Chain D Binding Site BS02

Receptor Information
>6h77 Chain D (length=301) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRVRIEKMSSEVVDSNPYSRLMALKRMGIVSDYEKIRTFAVAIVGVGGVG
SVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPHQAGLSKVQAAEHTL
RNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCVDNF
EARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVV
AANIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGY
NAMQDFFPTMSMKPNPQCDDRNCRKQQEEYKKKVAALEIIHEDNEWGIEL
V
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6h77 Chain D Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6h77 An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C226 C229 C303 C308
Binding residue
(residue number reindexed from 1)		C191 C194 C268 C273
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008641 ubiquitin-like modifier activating enzyme activity

View graph for
Molecular Function
External links
PDB RCSB:6h77, PDBe:6h77, PDBj:6h77
PDBsum6h77
PubMed30412706
UniProtQ9GZZ9|UBA5_HUMAN Ubiquitin-like modifier-activating enzyme 5 (Gene Name=UBA5)

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