Structure of PDB 6foq Chain D Binding Site BS02

Receptor Information
>6foq Chain D (length=458) Species: 115828 (Streptomyces maritimus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTST
PDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSR
RLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLS
RKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAF
EFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAP
PLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLP
YRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQL
ELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREG
YRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFR
LNQNIPPS
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain6foq Chain D Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6foq Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Resolution1.386 Å
Binding residue
(original residue number in PDB)		L117 G134 V136 T139
Binding residue
(residue number reindexed from 1)		L113 G130 V132 T135
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H78 S137 T245
Catalytic site (residue number reindexed from 1) H74 S133 T241
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding

View graph for
Molecular Function
External links
PDB RCSB:6foq, PDBe:6foq, PDBj:6foq
PDBsum6foq
PubMed29686059
UniProtQ9KHK2

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