Structure of PDB 6evj Chain D Binding Site BS02

Receptor Information
>6evj Chain D (length=708) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYS
DFHFIDLEGNTIVKENNAMLKHRFEIIEGQERNIAWTIVNSICNMTENSK
PRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSFDG
EEMATDDEYILDEESRARIKTRLFVLRQELATAGLWDSFRQSEKLEEEFS
YPPTFQRLANQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQ
IESFDPRTIRELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKD
AKACLDTFWGWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLK
KTNHLKWGLGEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEF
NKASELTNSNWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMK
AVYINTALLNSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHL
RNDTDVVNFISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPV
YLYVRTNGTSKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPF
FRNRENDWPIGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAE
SRKLLLLIQAFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFL
KAVQLSMG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6evj Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
H326 K328 W363 G366 G368 Q369 A370 P371 K373 Y388 P393 R503 H505 V512 N514 K534 R561 T562 N563 G564 K569
Binding residue
(residue number reindexed from 1)
H320 K322 W357 G360 G362 Q363 A364 P365 K367 Y382 P387 R497 H499 V506 N508 K528 R555 T556 N557 G558 K563
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0039694 viral RNA genome replication
GO:0075523 viral translational frameshifting

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Molecular Function

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Biological Process
External links
PDB RCSB:6evj, PDBe:6evj, PDBj:6evj
PDBsum6evj
PubMed29202182
UniProtH6QM92

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