Structure of PDB 6chv Chain D Binding Site BS02

Receptor Information
>6chv Chain D (length=91) Species: 585 (Proteus vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVSHPGEMIARDLEDMGVSGRRFAHNIGVTPATVSRLLAGKTALTPSLSI
RIAAALGSTPEFWLRLQSNYDLRQLENQIDTSGIVLYGESN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6chv Structural basis of transcriptional regulation by the HigA antitoxin.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		S23 G24 R25 S39
Binding residue
(residue number reindexed from 1)		S19 G20 R21 S35
Binding affinityPDBbind-CN: Kd=125nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
GO:0097351 toxin sequestering activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6chv, PDBe:6chv, PDBj:6chv
PDBsum6chv
PubMed30793388
UniProtQ7A224|HIGA_PROVU Antitoxin HigA (Gene Name=higA)

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