Structure of PDB 5zm3 Chain D Binding Site BS02

Receptor Information
>5zm3 Chain D (length=285) Species: 1549217 (Aspergillus stellatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMPPIRRVNASQGSDAAYQILQEDGCVIVEQVICPNIIAKISDDVNRVMD
KATIGAKKGEQTHIINMHNRTIHMGDLVLTSKTYRDELLNLPFAHEVLEK
VFKKDSGDYWLNMGNILNMLPGAEAQRPHRDDYLYPVSQHMDPATSPDLM
INITFPLNEFRHDNGGTLLLPKSHTGPNADFYANAEDLPAAEMQVGDALI
FTGKCVHGGGANRSDKPRIGLALAAQPGYLTPRESNVNVPRDIVETMTPL
AQRMIGWGTVRTKDTYGLNMLQDKDFHEALGLKSK
Ligand information
Ligand IDAKG
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385OC(=O)CCC(=O)C(O)=O
FormulaC5 H6 O5
Name2-OXOGLUTARIC ACID
ChEMBLCHEMBL1686
DrugBankDB08845
ZINCZINC000001532519
PDB chain5zm3 Chain D Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zm3 Structural and Computational Bases for Dramatic Skeletal Rearrangement in Anditomin Biosynthesis.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		Q132 H213 G215 R224
Binding residue
(residue number reindexed from 1)		Q126 H207 G209 R218
Annotation score4
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0016114 terpenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5zm3, PDBe:5zm3, PDBj:5zm3
PDBsum5zm3
PubMed29972643
UniProtA0A097ZPD5|ANDA_EMEVA Dioxygenase andA (Gene Name=andA)

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