Structure of PDB 5wql Chain D Binding Site BS02

Receptor Information
>5wql Chain D (length=647) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRY
LNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRF
ERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDE
LSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDP
HTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSK
AISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGK
GTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVK
VQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNG
KVREDSDTQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFG
AGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTP
DIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHN
ARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLAR
LNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKAR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5wql Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc
Resolution2.3 Å
Binding residue
(original residue number in PDB)		G247 I248 G249 A250 V251 L252 I307 K308
Binding residue
(residue number reindexed from 1)		G223 I224 G225 A226 V227 L228 I283 K284
Enzymatic activity
Enzyme Commision number 3.4.21.102: C-terminal processing peptidase.
Gene Ontology
Molecular Function
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5wql, PDBe:5wql, PDBj:5wql
PDBsum5wql
PubMed29138488
UniProtP23865|PRC_ECOLI Tail-specific protease (Gene Name=prc)

[Back to BioLiP]