Structure of PDB 5w7b Chain D Binding Site BS02

Receptor Information
>5w7b Chain D (length=412) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDS
DKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIIL
LGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLD
SENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPA
IVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHV
ILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWM
SANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQ
KMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNP
QIEEVFGDQGGH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5w7b Chain D Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w7b Crystal structure of the mammalian lipopolysaccharide detoxifier.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D185 D187 D204 N206 D209 V212
Binding residue
(residue number reindexed from 1)		D27 D29 D46 N48 D51 V54
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.77: acyloxyacyl hydrolase.
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0050528 acyloxyacyl hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5w7b, PDBe:5w7b, PDBj:5w7b
PDBsum5w7b
PubMed29343645
UniProtO18823|AOAH_RABIT Acyloxyacyl hydrolase (Gene Name=AOAH)

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