Structure of PDB 5vzu Chain D Binding Site BS02

Receptor Information
>5vzu Chain D (length=417) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCRE
EYGVCENLRKLEITGVSCRDVYAKLLHRYRHILGLWQPDIGPYGGLLNVV
VDGLFIIGWMYLPPHDPHVDDPMRFKPLFRIHLMERKAATVECMYGHKGP
HHGHIQIVKKDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIFH
EHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLIKPGLFKGTYGSHG
LEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQRNF
NELSRIVLEVRERVRQEQQEGQPFVLPVGVSSRNEDYPRTCRMCFYGTGL
IAGHGFTSPERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADAP
SPQAFDEMLKNIQSLTS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5vzu Chain D Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vzu Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		C206 H214 C230 H236
Binding residue
(residue number reindexed from 1)		C143 H151 C167 H173
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5vzu, PDBe:5vzu, PDBj:5vzu
PDBsum5vzu
PubMed29279382
UniProtQ5XUX0|FBX31_HUMAN F-box only protein 31 (Gene Name=FBXO31)

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