Structure of PDB 5vnz Chain D Binding Site BS02

Receptor Information
>5vnz Chain D (length=111) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQQGYDVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDT
GQKCPVDNEVLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKH
LSQCRFALEHH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5vnz Chain D Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5vnz The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.
Resolution3.41 Å
Binding residue
(original residue number in PDB)		C86 H88 C106 D109
Binding residue
(residue number reindexed from 1)		C34 H36 C54 D57
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0005164 tumor necrosis factor receptor binding
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5vnz, PDBe:5vnz, PDBj:5vnz
PDBsum5vnz
PubMed29176576
UniProtQ6IWL4|TRAF6_DANRE TNF receptor-associated factor 6 (Gene Name=traf6)

[Back to BioLiP]