Structure of PDB 5un8 Chain D Binding Site BS02

Receptor Information
>5un8 Chain D (length=429) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKSNMLYSPQMALKLALTEWLQEFSVT
LEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAKFE
EMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRS
HSSAQFLIGDQEPWAFRGGLAGEFQRLLP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5un8 Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Resolution2.13 Å
Binding residue
(original residue number in PDB)
Y69 N175 T222
Binding residue
(residue number reindexed from 1)
Y11 N117 T164
Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
External links
PDB RCSB:5un8, PDBe:5un8, PDBj:5un8
PDBsum5un8
PubMed28319083
UniProtO60502|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)

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