Structure of PDB 5ue9 Chain D Binding Site BS02

Receptor Information
>5ue9 Chain D (length=262) Species: 1360 (Lactococcus lactis subsp. lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASML
LRRPISISSWDKVAKTCTILYRIGDETSGTYEISKLQSGAKIDVMGPLGN
GFPVDEVVSTDKILIVGGGIGVPPLYELAKQLEEKNCQMTILLGFASEKV
KILEKEFAELKNVSLKIATDDGSYGTKGHVGMLMEEIDFEVDALYTCGAP
AMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKEDENHALKVCE
DGPVFLGKQLLL
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain5ue9 Chain D Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ue9 Isoleucine 74 Plays a Key Role in Controlling Electron Transfer Between Lactococcus lactis Dihydroorotate Dehydrogenase 1B Subunits
Resolution2.72 Å
Binding residue
(original residue number in PDB)		M224 C226 G227 G229 A230 C231 Y232 C234 C249
Binding residue
(residue number reindexed from 1)		M224 C226 G227 G229 A230 C231 Y232 C234 C249
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050660 flavin adenine dinucleotide binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0044205 'de novo' UMP biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5ue9, PDBe:5ue9, PDBj:5ue9
PDBsum5ue9
PubMed
UniProtQ9CFW7|PYRK_LACLA Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit (Gene Name=pyrK)

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