Structure of PDB 5kq1 Chain D Binding Site BS02
Receptor Information
>5kq1 Chain D (length=122) Species:
284812
(Schizosaccharomyces pombe 972h-) [
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MEDENILRNAVNLQVLKFHYPEIESIIDIASHVAVYQFDVGSQKWLKTSI
EGTFFLVKDQRARVGYVILNRNSPENLYLFINHPSNVHLVDRYLIHRTEN
QHVVGLWMFDPNDMSRIFNIVK
Ligand information
>5kq1 Chain F (length=21) Species:
9606
(Homo sapiens) [
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PPSPSVLPKPPSHWVPVSFNP
Receptor-Ligand Complex Structure
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PDB
5kq1
Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Resolution
3.002 Å
Binding residue
(original residue number in PDB)
Y36 F38 V40 Q43 W45 K47 S85 N86 H88 Y93 R97 W107
Binding residue
(residue number reindexed from 1)
Y36 F38 V40 Q43 W45 K47 S85 N86 H88 Y93 R97 W107
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0005515
protein binding
GO:0008047
enzyme activator activity
GO:0170008
mRNA phosphatase activator activity
Biological Process
GO:0000184
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290
deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000956
nuclear-transcribed mRNA catabolic process
GO:0006397
mRNA processing
GO:0043085
positive regulation of catalytic activity
GO:0110156
mRNA methylguanosine-cap decapping
Cellular Component
GO:0000932
P-body
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0010494
cytoplasmic stress granule
GO:0098745
RNA decapping complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5kq1
,
PDBe:5kq1
,
PDBj:5kq1
PDBsum
5kq1
PubMed
27694842
UniProt
Q9P805
|DCP1_SCHPO mRNA-decapping enzyme subunit 1 (Gene Name=dcp1)
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