Structure of PDB 5jk0 Chain D Binding Site BS02

Receptor Information
>5jk0 Chain D (length=349) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQ
ACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFNS
LKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKS
YIYNITLKNISKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIV
FTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLK
EWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGA
HMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHRLEEAASIWEE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jk0 Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
K62 R65 N66 S121 A123 T124 N127 S193 R199 N277 Q278 T284 A286 Y287 H335 A336
Binding residue
(residue number reindexed from 1)
K62 R65 N66 S121 A123 T124 N127 S185 R191 N269 Q270 T276 A278 Y279 H327 A328
Binding affinityPDBbind-CN: Kd=150nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0009037 tyrosine-based site-specific recombinase activity
Biological Process
GO:0006310 DNA recombination
GO:0007059 chromosome segregation
GO:0015074 DNA integration
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5jk0, PDBe:5jk0, PDBj:5jk0
PDBsum5jk0
PubMed28009253
UniProtO25386|XERH_HELPY Tyrosine recombinase XerH (Gene Name=xerH)

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