Structure of PDB 5hrq Chain D Binding Site BS02

Receptor Information
>5hrq Chain D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>5hrq Chain G (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB5hrq 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation.
Resolution1.28 Å
Binding residue
(original residue number in PDB)
F1 V2 H5
Binding residue
(residue number reindexed from 1)
F1 V2 H5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:5hrq, PDBe:5hrq, PDBj:5hrq
PDBsum5hrq
PubMed28598606
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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