Structure of PDB 5h7r Chain D Binding Site BS02

Receptor Information
>5h7r Chain D (length=124) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLCAVCGQAHSLEENHFYSYPEEVDDDLICHICLQALLDPLDTPCGHTYC
TLCLTNFLVEKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHC
TQVLQRCDLEHHFQTSCKGASHYG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5h7r Chain D Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5h7r Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		C31 C34 C51 C54
Binding residue
(residue number reindexed from 1)		C30 C33 C50 C53
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5h7r, PDBe:5h7r, PDBj:5h7r
PDBsum5h7r
PubMed29496391
UniProtQ8TBB1|LNX1_HUMAN E3 ubiquitin-protein ligase LNX (Gene Name=LNX1)

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