Structure of PDB 5dnn Chain D Binding Site BS02

Receptor Information
>5dnn Chain D (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>5dnn Chain J (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagatactaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctgattcagctgaacatgccttttgatggagc
agtttccaaatacacttttggtagtatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB5dnn Allosteric cross-talk in chromatin can mediate drug-drug synergy
Resolution2.8 Å
Binding residue
(original residue number in PDB)		K28 R30 K31 E32 S33 Y37
Binding residue
(residue number reindexed from 1)		K1 R3 K4 E5 S6 Y10
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:5dnn, PDBe:5dnn, PDBj:5dnn
PDBsum5dnn
PubMed28358030
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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