Structure of PDB 5czr Chain D Binding Site BS02

Receptor Information
>5czr Chain D (length=216) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNVAPKFLANMTSVILPEDLPVGAQAFWLVAEDQDNDPLTYGMSGPNAYF
FAVTPKTGEVKLASALDYETLYTFKVTISVSDPYIQVQREMLVIVEDRND
NAPVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPS
TGDSEHLFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTI
QCSLPVFLSISVVDQP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5czr Chain D Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5czr Crystal Structure of Human Protocadherin-24 EC1-2
Resolution2.3 Å
Binding residue
(original residue number in PDB)		E17 D66 E68 D99
Binding residue
(residue number reindexed from 1)		E18 D67 E69 D100
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5czr, PDBe:5czr, PDBj:5czr
PDBsum5czr
PubMed
UniProtQ9BYE9|CDHR2_HUMAN Cadherin-related family member 2 (Gene Name=CDHR2)

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